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Inventi Impact: Pharmacokinetics & Pharmacodynamics

Articles

  • Inventi:pkd/30742/19
    Pharmacokinetic Profile and Anti-Adhesive Effect of Oxaliplatin-PLGA Microparticle-Loaded Hydrogels in Rats for Colorectal Cancer Treatment
    Research 2020 : January - March
    Sharif Md Abuzar, Jun-Hyun Ahn, Kyung Su Park, Eun Jung Park, Seung Hyuk Baik, Sung-Joo Hwang

    Colorectal cancer (CRC) is one of the most malignant and fatal cancers worldwide.\nAlthough cytoreductive surgery combined with chemotherapy is considered a promising therapy,\nperitoneal adhesion causes further complications after surgery. In this study, oxaliplatin-loaded\nPoly-(d,l-lactide-co-glycolide) (PLGA) microparticles were prepared using a double emulsion method\nand loaded into hyaluronic acid (HA)- and carboxymethyl cellulose sodium (CMCNa)-based\ncross-linked (HC) hydrogels. From characterization and evaluation study PLGA microparticles\nshowed smaller particle size with higher entrapment efficiency, approximately������

    How to Cite this Article
    Attribution/ CC Compliant Citation: Abuzar, Sharif Md, et al. \"Pharmacokinetic Profile and Anti-Adhesive Effect of\nOxaliplatin-PLGA Microparticle-Loaded Hydrogels in Rats for Colorectal Cancer Treatment.\" Pharmaceutics 11.8 (2019):\n392.\nhttps://doi:10.3390/pharmaceutics11080392\nhttp://creativecommons.org/licenses/by/4.0/\n\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.\n
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